Priligy (generic name: dapoxetine; brand names include: Poxet, Prejac, Extensil, Duratia, Daposun, Dapoligy, Vriligy) belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs).
Priligy is used to combat the effects of premature ejaculation. It only needs to be taken an hour or two before sexual intercourse for the user to feel the benefits of the drug.
Priligy is the only drug with regulatory approval for such treatment. Currently, it is approved for use in several European countries including Finland, Sweden, Portugal, Austria, Germany, Italy and Spain. Approvals for Priligy are anticipated in other countries as well.
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Dapoxetine (Priligy) clinical trials
Clinical trials of Dapoxetine covered 2,614 men in the age group of 18-77 years having premature ejaculation problems. These men, who retained monogamous sexual bond with their partners for six months or more, were given 30 mg or 60 mg of Dapoxetine or a placebo daily for a period of more than three months or 12 weeks. At the end of the period, it was found that men who were given Dapoxetine not only experienced a three-fold increase in the duration of sexual intercourse, but also more pleasure from their sexual activity. According to Dr. Richard Longwell, chairman and managing director of the Department of Urologic Surgery at the University of Minnesota, the development of Dapoxetine puts an end to the frustration of men with premature ejaculation problems and also that of their sexual partners. He asserted that Dapoxetine not only inhibits orgasm, but also increases sexual satisfaction. In the clinical trial mentioned above the percentage of men rating control over ejaculation as “OK to awesome” enhanced from a mere 2.5 per cent before taking Dapoxetine to 51.8 per cent after taking it. Dr. Longwell further observed that Dapoxetine was equally effective in delaying orgasm in men who prefer self sex. Among men who have sex with other people, the percentage of their partners who reported feeling satisfied by sex increased from 25 per cent without taking Dapoxetine to 47 per cent with the wonder drug. In fact, the potential social benefits of this Dapoxetine hydrochloride are considerable – it’s fast-acting while producing few side-effects.
Priligy (Dapoxetine) dosage
Dapoxetine or Priligy, the brand name of the drug in Europe, is to be taken only once in 24 hours. It is an oral pill that will be available only with valid prescriptions from qualified physicians. The normal dosage for Dapoxetine hydrochloride or Priligy is 30 mg or 60 mg depending on the patient and his premature ejaculation problems. However, the dosage may be increased to 100 mg later depending on the physician’s recommendation. Dapoxetine or Priligy pills are to be taken wholly with a glass of water one to one-and-a-half hours prior to sexual intercourse.
Priligy (Dapoxetine) side effects
Dapoxetine hydrochloride belongs to the SSRI family of drugs that have a short half-life. In other words, this means that the patients’ plasma receives it quickly and the plasma levels are normal again after about 1-2 hours. Nevertheless, premature ejaculation treatment with Dapoxetine is not free of side effects. The most common aftereffects of using Dapoxetine hydrochloride include nausea, headache, diarrhea and dizziness. While 8.7 per cent men taking low dose (30 mg) Dapoxetine experienced nausea, 20.1 per cent of men using high dose (60 mg or 100 mg) of the drug had the problem. In fact, during the studies it was found that the side effects were more frequent in patients using Dapoxetine 100 mg (16.1 per cent) compared to those taking Dapoxetine 60 mg (5.6 per cent). Depending on this reaction and acceptability of the drug, scientists used the 60 mg dose of Dapoxetine for the study that is continuing on a large-scale.
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